Which equipment should always be used when withdrawing solution from an ampule?

When withdrawing a solution from an ampule, the use of a sterile filter straw is vital to ensure the safety and integrity of the compounded sterile product. A sterile filter straw provides a mechanism that allows for the aspirating of the solution while simultaneously filtering out any potential glass particles that may have been created if the ampule was broken. This is particularly important due to the nature of ampules, which are often made of glass and can produce shards when opened.

Using a sterile filter straw helps to prevent contamination and ensures that only the sterile solution is drawn into the syringe, thereby maintaining the required sterility of the compounded preparation. This is crucial in sterile compounding settings where the risk of infection must be minimized, and patient safety is paramount.

Other methods, such as a syringe or vented transfer set, may not offer the same level of protection from potential particulate contamination, and while they may be used for withdrawing solutions from other types of containers, the specific characteristics of ampules necessitate a filter straw for safe and effective withdrawal.