Which type of drugs are compounded in a positive pressure room?

Compounding nonhazardous drugs in a positive pressure room is based on the need to maintain a sterile environment that minimizes the risk of contamination. Positive pressure rooms are designed to have a higher pressure inside compared to the surrounding areas, which helps prevent outside air (and any contaminants it may carry) from entering the space.

This is particularly important when working with nonhazardous drugs, which, while typically considered safer than hazardous drugs, still require careful control of environmental conditions to ensure the final product's safety and efficacy. The sterile environment is essential for nonhazardous compounding, especially when preparing injectable medications or other formulations that must be free from microbial contamination.

In contrast, hazardous drugs are compounded in negative pressure rooms to contain any dangerous agents and prevent exposure to personnel and the environment. High-risk drugs might also require specific precautions, and controlled substances are governed by additional regulatory requirements, but those factors do not pertain directly to the use of positive pressure environments for compounding purposes. Therefore, compounding nonhazardous drugs in a positive pressure room is the correct focus for this question.